I've been playing the crap out of Political Machine v. 1.0 (I know, I know--there have been two updates since then, and a third one on the way--I told myself I wanted to play through 1.0 as thoroughly as possible before seeing what's in the newer versions). I've now beaten every Republican as every Democrat and vice versa. I also created a custom candidate and had him beat everybody with 500+ electoral votes.
Then I got it in my head that I wanted my custom candidate to get a perfect 538-0 against a human (non-Meteor) candidate. The hardest part was flipping WY/UT, but I pulled it off against Romney (I blacked out my candidate's name because it's my IRL name):
It's been a ton of fun! I think the final thing I'll do before updating to a newer version is create a Republican custom candidate and beat all the Democrats, have all the Democrats beat him, and then culminate with my two custom candidate squaring off against each other!