Honestly I can't imagine playing GTA 4 for that long...I would shoot my self in the head. Besides I have played Elderscrolls 4: Oblivion for 53 hours straight and maybe a total of 1300 hours since I bought it.
*Edit, added 20 plus hours on accident. I'm not sure if the human body can look at a computer screen that long and not start seeing meatspin.*